This is not just skincare — it’s skin science. Developed by longevity experts to target visible aging at the cellular level, it restores firmness, smooths wrinkles, boosts collagen, and strengthens the skin barrier — without compromise. A new era of skin transformation starts now.


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EllieVate Skin+
Topical Rejuvenating Serum
$149
$129
2-month supply*FREE SHIPPING
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An exclusive formula that gives exquisite results!
Key Ingredients
Combined with Advanced Absorption Technology that enhances penetration of active ingredients into deeper layers where true transformation begins. Click on an ingredient to learn more.

What We Are Proud Of
Formulated With Science And Love
Creating this formulation has been a true labor of love. With a background in longevity science, years of experience designing personalized prescription skincare, and leading a prescription-grade skincare company, I knew exactly what it would take to create something truly different.
I refused to compromise — on ingredients, on quality, or on results. Every decision behind this formula was intentional, rooted in science, and made with the highest standards in mind. This product represents everything I believe about aging well, skin health, and true cellular rejuvenation, and I’m so proud to finally share it with you.
I hope you love it as much as I do, and that it helps you achieve the beautiful, healthy skin you deserve.


Important Information
Scientific Sources
Frequently Asked Questions
Find answers to common questions about EllieMD.
EllieVate Skin+ is a clinically formulated, prescription-grade serum that combines science-backed active ingredients with luxury-grade cosmetic components. It's designed to address visible signs of aging - including fine lines, dullness, loss of firmness, and uneven texture - by targeting the skin at the cellular level.
Each bottle contains:
- Tretinoin 0.027% - A gold-standard retinoid that accelerates cellular turnover, fades discoloration, and smooths fine lines.
- GHK-Cu (Copper Tripeptide-1) 1% - A potent copper peptide that supports collagen production and skin repair.
- NAD+ (Nicotinamide Adenine Dinucleotide) 0.5% - A coenzyme that replenishes cellular energy and improves skin renewal.
- Spilanthol (Acmella Oleracea Extract) 1% - A natural muscle relaxant that softens expression lines around the eyes, mouth, and forehead.
- Niacinamide 5% - Strengthens the skin barrier, reduces redness and pigmentation, and improves elasticity.
- Magnesium Ascorbyl Phosphate (Vitamin C) 3% - A stable form of Vitamin C that brightens skin and stimulates collagen production.
- Hyaluronic Acid 1% - Deeply hydrates and plumps the skin using low- and medium-molecular weight molecules.
- PhytoCellTec™ Exosomes 0.4% - Plant stem cell-derived extracellular vesicles that enhance collagen synthesis and barrier function.
All actives are delivered using our proprietary EllievaTec™ absorption technology, ensuring deep dermal penetration and maximum effectiveness.
This is not a personalized formula - it's one universal, expertly crafted treatment designed to deliver exceptional results across skin types when used as directed.
Apply 2 full pumps of EllieVate Skin+ to clean, dry skin every evening before bed. Gently massage the serum into your face, avoiding the eyes, lips, and any broken skin. Always follow with a gentle moisturizer if needed and apply broad-spectrum SPF daily.
Because this is an airless pump bottle, it may take a few initial pumps to release product, especially if it's your first time using it. This is normal - continue pressing down until the serum dispenses.
If your skin feels sensitive or dry when starting out, you can apply it every other night for the first 1–2 weeks as your skin adjusts.
You may be experiencing what's known as purging - a temporary and common response to active ingredients like Tretinoin.
Here's what's happening:
Tretinoin accelerates your skin's natural exfoliation process, increasing cell turnover and bringing underlying debris, oil, and bacteria to the surface more quickly than usual. This can trigger breakouts, redness, flaking, or inflammation, even if you haven't broken out in a while.
This is not a bad reaction - it's your skin clearing out what's been sitting below the surface.
For some, purging begins around week 1 or 2 and may last up to 6 weeks. After this period, your skin typically stabilizes and begins to visibly improve.
Tips to manage the purging phase:
- Reduce usage -Try applying EllieVate Skin+ every other night instead of nightly.
- Be gentle -Avoid exfoliants, scrubs, or any products with harsh actives.
- Hydrate -Use a fragrance-free, barrier-repair moisturizer.
- Don't pick -Picking or popping can lead to scarring or prolong inflammation.
- Reach out - If you're unsure or symptoms persist beyond 8 weeks, contact us. Our team is here to support your skin journey.
Most users begin to notice improvements in 4 to 8 weeks, with optimal results continuing over 3 to 6 months. Results may include smoother texture, improved firmness, reduced fine lines, and a brighter, more even tone.
Consistency is key. Your skin is being reprogrammed at a cellular level - and real change takes time.
The blue color comes from GHK-Cu, a naturally occurring copper peptide that has a distinct bluish hue. This ingredient plays a powerful role in collagen production and skin regeneration - and the color is a visible sign of its presence and potency.
EllieVate Skin+ was formulated for normal, dry, combination, and oily skin. However, due to the potency of prescription-grade ingredients like Tretinoin and NAD+, it may not be suitable for:
- People with rosacea or active eczema/psoriasis flares
- Those with extremely sensitive or compromised skin barriers
- Anyone who is pregnant or breastfeeding
- Individuals allergic to retinoids, copper peptides, or any formula component
- If you're unsure, we recommend consulting with your provider before beginning use.
Mild side effects may include dryness, flaking, redness, tightness, or sensitivity, especially in the first 2-4 weeks. These symptoms are common with actives like Tretinoin and NAD+ and usually subside as your skin builds tolerance.
Using a gentle moisturizer and sunscreen can help reduce discomfort. If you experience persistent is burning, swelling, or rash, discontinue use and contact your provider.
Yes - but keep your routine simple and supportive. We recommend:
- Gentle cleanser
- EllieVate Skin+ (PM only)
- Moisturizer
- SPF (AM)
Avoid using additional exfoliants, acids, or retinoids while using EllieVate Skin+ to prevent over-irritation.
Yes. EllieVate Skin+ includes regulated prescription ingredients like Tretinoin, which require a provider's review and approval. After completing a short online medical intake, a licensed clinician will determine if the formula is right for you.
Your EllieVate Skin+ serum is compounded in the United States at a licensed 503A compounding pharmacy. These pharmacies are regulated by state boards of pharmacy and the FDA and are authorized to produce customized prescription medications based on a provider's order. Each bottle is freshly compounded to ensure potency, purity, and quality.
No. EllieVate Skin+ is free from artificial fragrances, synthetic dyes, parabens, phthalates, and other commonly irritating or hormone-disrupting additives. We believe in high-efficacy, low-irritation formulations that respect your skin - and your health.
We believe in transparency - here is the complete ingredient deck in EllieVate Skin+:
Aqua (Water), Niacinamide, Magnesium Ascorbyl Phosphate, Copper Tripeptide-1 (GHK-Cu), Alcohol, Acmella Oleracea Flower Extract (Spilanthol), Cetearyl Alcohol, Polyacrylamide & C13-14 Isoparaffin & Laureth-7, Phosphatidyl Choline, Phenoxyethanol, Caprylyl Glycol, Sodium Hyaluronate, Nicotinamide Adenine Dinucleotide (NAD+), Lycium barbarum Callus Culture Extract (and) Isomalt (and) Lecithin (and) Water, Retinoic Acid (Tretinoin), Magnesium Chloride, Phenethyl Alcohol.
- No artificial dyes or added colorants
- No parabens
- No phthalates
- Phosphatidyl Choline is derived from Non-GMO soy
Each ingredient was selected for safety, performance, and skin compatibility - backed by clinical science and compounding best practices.
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