It’s so important to talk freely about the realities of aging and how we experience hormone changes, dips in energy levels, and body composition shifts that can leave us feeling out of sync and alone. Bodies are amazing, but they can also be challenging. So when we have treatments like the Thrill Pill, that improve erectile dysfunction, enhance libido, and help strengthen human connections, we at EllieMD are pleased to openly discuss their benefits.

The newest product at EllieMD fits in our sexual wellness lineup that can help men and women alike reconnect with their partners, reignite with that spark of desire, enhance libido, and rekindle the physical processes needed for an active, healthy sex life.

The Thrill Pill is a combination of three active ingredients delivered in troche form—a small, hard tablet that dissolves under the tongue. Oxytocin, PT-141, and tadalafil act in concert to enhance libido, ignite passion, and boost sexual satisfaction.

This recipe of medications has shown to be a particularly effective ED treatment for men experiencing certain types of treatment-resistant erectile dysfunction.

Tadalafil is in a class of medications called phosphodiesterase 5 (PDE5) inhibitors, which is used to treat erectile dysfunction, certain prostate conditions, and pulmonary arterial hypertension. It’s method of action is to block the PDE5 enzyme, relaxing specific muscles for increased blood flow to certain areas of the body. The dosage determines the condition being treated.

For ED treatment, the pill is taken up to an hour before any desired intimacy begins, increasing blood flow to achieve an erection, and the effects of the medication may last up to 36 hours.

Oxytocin

This medication is a hormone and neurotransmitter produced by the hypothalamus and released by the pituitary gland. It’s sometimes referred to as the “love hormone,” because it can foster a sense of bonding, trust, empathy, and love, which strengthens a sense of connection, which helps enhance libido. Oxytocin can be produced naturally during sexual activity or even during simple touch. Oxytocin also reduces stress and anxiety.

PT-141

Its scientific name is bremelanotide, PT-141 is a synthetic peptide in the brain that improves ED and sexual desire. It’s prescribed as an ED treatment for men and for hypoactive sexual desire disorder (HSDD) treatment in women. PT-141 creates enhanced libido through central nervous system stimulation rather than simply increasing blood flow to the genital region. It is often prescribed as an alternative to traditional sexual dysfunction medications for people with treatment-resistant ED.

This versatile hormone manages appetite, cravings, and satiety and influences the reward pathways within the brain. It’s also a significant regulator of social behaviors, relaxing away anxieties and fears while stimulating feel-good emotions. In this way, oxytocin is an important component for improving the psychological side of sexual desire disorders and erectile dysfunction. As an important piece of social conditioning, oxytocin helps people bond, improve eye contact, recognize emotion, build trust, and increase feelings that not only enhance libido but also facilitate positive emotions foundational to relationship building.

PT-141 provides the sensation component of the Thrill Pill, increasing physical arousal and sensitivity to the sexual organs by improving blood circulation, which enhances function and physical responsiveness. It works directly on the central nervous system, releasing nitric oxide in the brain to activate melanocortin receptors, which leads to a feedback loop of increased sexual desire, enhanced libido, and improved physical responses.

Because of its distinctive method of action, PT-141 has proven in clinical trials to be an effective treatment for patients who’ve been unresponsive or resistant to existing ED treatments, including diabetic or post-prostatectomy ED patients, especially when combined with other forms of ED enhancement.

Tadalafil’s flexibility in dosage allows for improved erectile quality as well as altered sensory feedback during intercourse, which can even, in some cases, delay ejaculation. Since a large component of sexual dysfunction is psychological, the improvement to performance and sensation can lead to greater satisfaction with a person’s relationship attachment and quality of live overall. In multiple conducted studies, success rates of tadalafil as an ED treatment hover around 70% regardless of dosage.

Troches deliver medicine by placing them under the tongue, where blood vessels are very close to the surface. This small, hard tablet dissolves slowly over around 30 minutes.

Bypassing the digestive system, troches instead deposit the medication directly into the bloodstream. Typical delivery interacts with digestive acids and is processed through the liver before entering the bloodstream, which can reduce bioavailability and increase irritation. Troches are a more liver-friendly option, especially for people with sensitive gut conditions such as ulcerative colitis or irritable bowel syndrome. Medicine via troche delivery reduces exposure to the gut microbiome.

Patients who also have difficulty swallowing may also benefit from troche delivery.

Benefits to be determined, but a few of them will be:

• Enhanced libido: sexual dysfunction can be a disheartening, multi-layered problem to face, not just physical but psychological. A treatment providing both physical and mental benefits has a better chance of being successful than others on the market.
• Better quality erections: Not all erections are created equal. Having an erection capable of performing as desired is a confidence builder and leaves all partners experiencing pleasure and closeness.
• Increased blood flow and sensitivity: While it’s not only about the physical, that’s a large component of ED treatment. Greater sensitivity and circulation makes room for a more satisfying experience for everyone who needs it.
• Delayed ejaculation and prolonged ejaculation latency period: Increased sensitivity may lead to concerns about premature climax. Lay those fears aside since tadalafil is shown to delay ejaculation in some cases.
• Moderated social behaviors to improve bonding and increase emotional recognition for romantic partners: The Thrill Pill is so much more than a superficial ED treatment intended to fix only the physical side of sexual dysfunction. Oxytocin is the “bonding hormone,” enhancing libido as well as emotions, trust, and connection with a valued partner.
• Increased physical arousal and sexual desire: Each of the above benefits culminates in physical arousal and the enhanced libido of sexual desire inherent in a successful sex life at any age.

The Thrill Pill is more than a corrective medication for sexual dysfunction; it’s a well-rounded treatment for the imbalances that occur during the aging process that negatively impact sexual function. Take back your sexual health and rekindle your passions with the Thrill Pill.

At EllieMD, we believe sexual health and wellness is vital to a high quality of life. There are many avenues for understanding and alleviating the source of sexual dysfunction, even resistant ED. Enhanced libido and ED treatment is only the beginning!

To learn more about the Thrill Pill and see if you qualify for a prescription, visit the product page to view our frequently asked questions or contact us to get started!