Growth hormones are an essential part of our systems and how we operate. We rely on them for healthy muscles, bones, energy, metabolism, and even more natural rhythms, even beyond childhood. Sermorelin, a synthetic peptide, stimulates the release of growth hormone from the pituitary gland, kickstarting a multitude of physiological functions that contribute to our overall health, wellness, and longevity.

The FDA approved sermorelin in 1997 as a treatment for growth hormone deficiencies in children. In 2008, sermorelin’s usage changed to include more purposes than the original FDA-approval due to research showing benefits beyond those for children. These expansions, while considered off-label, have been in practice for years and are considered safe under the supervision of medical professionals.

Sermorelin still fulfills its original purpose, stimulating growth hormone to promote bone growth and regulate protein, carbohydrate, and lipid metabolism. It also:

• Supports pituitary function
• Preserves pituitary hormone production

Research shows a natural decline of pituitary hormones with age. The longer sermorelin supports the pituitary gland, the slower that decline may be due to the stabilization of pituitary hormones.

How Does Sermorelin Work?

Sermorelin binds itself to the growth hormone releasing hormone receptor (GHRH) in order to copy the effects of natural growth hormone secretion. Through an interaction with an inhibitory hormone called somatostatin, sermorelin experiences a negative feedback cycle, which causes the pituitary gland to release bursts of human growth hormone (hGH).

This process mimics natural hormone rhythms, which over time support the body’s neuroendocrine system—typically the first system to experience age-related deterioration.

Sermorelin’s effects slow the aging process by supporting natural pituitary function and hormone levels of hGH. The result is extending youthful functionality and physiology.

Sermorelin’s potential advantages for wellness and longevity include:

• Muscle growth and repair
• Anti-aging effects
• Improved bone density
• Increased immune function
• Greater energy
• Better sleep quality

Research into sermorelin’s benefits for adults is still ongoing. Even now, advantages are still being uncovered. To maximize sermorelin’s potential, it’s best to use sermorelin supplements under a medical practitioner’s care.

Growth hormones benefit more than children. Certain body functions rely on growth hormones for the overall health and wellness of adults as well. Studies into the potential benefits growth hormones have on longevity are being conducted every day.

A sermorelin supplement to boost growth hormone levels in the body may bring benefits we have yet to uncover. At EllieMD, we offer sermorelin supplements under the supervision of qualified and licensed medical professionals.

Growth hormones for adults are important for the maintenance of lean muscles and reduction of body fat—particularly harmful, organ-smothering visceral fat found in the abdomen.

Bone density is another vital adult function of growth hormones, particularly for older adults. Preventing fractures and reducing the risk of osteoporosis become higher priorities as part of the aging process.

Pituitary health is also responsible for many functions, including stress responses, sodium and water balance, thyroid function, lean muscle-to-body-fat ratios, and skin pigmentation. Each of these concerns grows with adulthood and aging.

Incremental changes to the endocrine system can impact the speed at which ageing takes place, including how deeply the pituitary gland’s health impacts the signs of aging on the body.

Sermorelin’s support of the pituitary gland may have the potential to favor longevity with the right adaptations.

Because sermorelin does not occur naturally in the body, taking it in supplement form is the only way to benefit from its effects.

While research is ongoing, there have been studies that show a host of benefits from sermorelin supplements.

These include:

1. Enhanced muscle growth. In one study, muscle strength improved in elderly men given sermorelin injections, without significantly affecting body weight, BMI, or percent total fat mass.
2. Improved fat metabolism. A research study concerning insulin sensitivity as it relates to metabolic syndrome and its effect on abdominal obesity showed improved fat metabolism and a reduction in visceral abdominal fat after 1 year of growth hormone treatment.
3. Increased energy levels. A study conducted on athletes in Sydney, Australia concluded that the administration of growth hormone enhanced overall fitness performance thanks to reduced fat mass, increased lean body mass, and increased extracellular water. These functions resulted in increased sprint capacity and higher energy levels.
4. Better sleep quality. In a study on sleep deprivation and growth hormone, researchers tied growth hormone secretion to sleep patterns. After a period of sleep deprivation, the study subjects were permitted to sleep and their growth hormone levels monitored. High growth hormone levels supported the conclusion that higher secretion was the body’s attempt to compensate for lost sleep. Another study correlated high levels of GHRH with sleep stages, suggesting that greater growth hormone secretions suggested deeper sleep.
5. Anti-aging benefits. A study on patients with growth hormone deficiencies undergoing exogenous growth hormone therapy—a growth hormone only slightly different to what’s stimulated by sermorelin—discovered the patients experienced thicker epidermis and better sweat secretion. Both results are associated with healthier skin, showing what greater levels of growth hormone may be capable of producing in aging populations.

What so many of us are looking for in the quest for longevity and overall health is the opportunity to lead a long-lived and active lifestyle well into our later years. That involves having energy, the ability to move our bodies without fear of brittle bones or damaging muscles, the capability of getting a good night’s sleep, and the opportunity to appear on our outside as young as we feel on the inside.

The research suggests a sermorelin supplement to support pituitary gland function and stimulate growth hormone production is one way to achieve those longevity goals. With research continuing, these benefits and more are still being discovered!

To learn more about achieving better sleep quality, a more balanced body composition, and greater energy levels as well as other benefits, our sermorelin product pages are a great resource. We offer two supplementation methods—the sermorelin injection is a subcutaneous injection delivery with high bioavailability that bypasses the digestive system, or the sermorelin tablets are ideal for clients seeking a gentler delivery method. Both options are designed to support your wellness goals and help you feel your best, day and night!